Agouti Signaling Protein (ASIP) (Middle Region) Peptide
ASIP
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN5511781
Aperçu rapide pour Agouti Signaling Protein (ASIP) (Middle Region) Peptide (ABIN5511781)
Antigène
ASIP
(Agouti Signaling Protein (ASIP))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- Middle Region
-
Séquence
- CFFTANSHLP PEEKLRDDRS LRSNSSVNLL DVPSVSIVAL NKKSKQIGRK
-
Attributs du produit
- This is a synthetic peptide designed for use in combination with anti- ASIP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Stock
- -20 °C
-
Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- ASIP (Agouti Signaling Protein (ASIP))
-
Sujet
-
In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes.
Alias Symbols: ASP, AGSW, AGTI, AGTIL, SHEP9
Protein Size: 132 -
ID gène
- 434
-
NCBI Accession
- NM_001672, NP_001663
-
UniProt
- P42127
Antigène
-
Vous êtes ici:
